Dual effect of a Tn insertion into the gene Free

Abstract

Summary: The most common effect of transposon insertion is the inactivation of genes. However, in some cases, transposons can activate the expression of genes in the neighbourhood of their integration site. We previously described an insertion of the transposon Tn into the locus. and encode respectively a negative and a positive regulator involved in induction by sucrose of the exoenzyme levansucrase. Data in this paper show that the Tn insertion had two effects: it inactivated and it increased the transcription of . The latter effect involved one or several elements internal to the transposon.

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1991-01-01
2024-03-28
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