1887

Abstract

The ability of to protect mice against intestinal pathology caused by toxinogenic was studied. Different regions of the intestine of experimental mice were prepared for observation by scanning electron microscopy or homogenized for enumeration and quantification of toxin A by enzyme immunoassay and toxin B by cytotoxicity. The test group was treated for 6 d with an suspension in drinking water and challenged with on day 4. The three control groups were: axenic mice, mice treated with only and mice only challenged with The results showed that: (i) 70% of the mice infected by survived when treated with ; (ii) the -induced lesions on the small and large intestinal mucosa were absent or markedly less severe in -treated mice; and (iii) there was no decrease in the number of but rather a reduction in the amount of toxins A and B in -treated mice.

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1990-06-01
2021-08-02
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