1887

Abstract

Mutants of the obligatorily aerobic yeast , obtained by treating wild-type cells with -methyl--nitro--nitrosoguanidine, were selected on fructose medium containing 1% 2-deoxy--glucose. One mutant, designated R, displayed a significantly decreased initial rate of uptake of -glucose, 2-deoxy--glucose, -galactose and -xylose, and was unable to accumulate the latter three sugars. However, the residual monosaccharide transport was still energy-dependent. The mutant displayed significantly altered transport parameters for -glucose and -xylose. These results are evidence for the isolation of a mutant defective in the glucose carrier.

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1990-10-01
2021-05-15
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