SUMMARY: Aspartokinase activity was detected in extracts from (recovered from armadillo liver) and in grown axenically and Homoserine dehydrogenase activity was only detected in and in grown axenically. Activities, when detected, were 50 to 70% lower in or grown than in axenically grown In these two pathogenic mycobacteria, aspartokinase and homoserine dehydrogenase are subject to feedback inhibition by methionine - an additional regulator over those observed for the enzymes from Intact mycobacterium incorporated carbon from [U-C]aspartate into the aspartate family of amino acids (threonine, isoleucine, methionine and lysine) though the rate of incorporation in grown was about half that in grown axenically.


Article metrics loading...

Loading full text...

Full text loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error