1887

Abstract

Clinical isolates of were shown by Southern blotting to contain DNA sequences hybridizing to a probe derived from a plasmid. Two such DNA fragments, isolated from a gene library, were used as probes to show restriction fragment length polymorphism in strains by detecting a repetitive sequence apparently located at different points on the chromosome. This could indicate the presence of a transposable element in which is partly homologous to a region of the plasmid. The probes described can be used to fingerprint isolates, and in addition are capable of distinguishing from and BCG.

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1989-09-01
2024-04-18
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