1887

Abstract

Two adherence assays involving isolated mucosal cells or mucosal explants were used to study the adherence of five strains to murine gastrointestinal mucosal surfaces. Adherence was found to be dependent on the strain used, and on the cellular arrangement, as well as the site of origin of the mucosal surface. Adherence of strains NCPF 3436 and 3310 to stomach and jejunal surfaces was affected by the pH of the medium. Binding between the strains and stomach mucosal cells fluctuated as the pH was raised from pH 1·2 to pH 3·4. However, adherence increased with a rise in pH when the strains were incubated with stomach mucosal explants. Optimal adherence by both strains to jejunal mucosal surfaces occurred at neutral pH.

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1989-08-01
2021-05-14
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References

  1. Anderson M.L., Odds F.C. 1985; Adherence of Candida albicans to vaginal epithelia: significance of morphological form and effect of ketoconazole.. Mykosen 28:531–540
    [Google Scholar]
  2. Armitage P. 1973 Statistical Methods in Medical Research,, 2nd edn.. pp 32–33 New York: John Wiley & Sons;
    [Google Scholar]
  3. Barrett-Bee K., Hayes Y., Wilson R.G., Ryley J.F. 1985; A comparison of phospholipase activity, cellular adherence and pathogenicity of yeasts.. Journal of General Microbiology 131:1217–1221
    [Google Scholar]
  4. Bibel D.J., Aly R., Lahti L., Shinefield H.R., Maich H.I. 1987; Microbial adherence to vulvular epithelial cells.. Journal of Medical Microbiology 23:75–82
    [Google Scholar]
  5. Centeno A., Davis C.P., Cohen M.S., Warren M.M. 1983; Modulation of Candida albicans attachment to human epithelial cells by bacteria and carbohydrates.. Infection and Immunity 39:1354–1360
    [Google Scholar]
  6. Collins C.H., Lyne P.M. 1976; Culture Media.. In Microbiological Methods, 4th edn, pp 113–158 London: Butterworths;
    [Google Scholar]
  7. Cox F. 1986; Candida albicans adherence in newborn infants.. Journal of Medical and Veterinary Mycology 24:121–125
    [Google Scholar]
  8. Demaria A., Buckley H., Von Lichtenstein F. 1976; Gastrointestinal candidiasis in rats treated with antibiotics, cortisone and azathioprine.. Infection and Immunity 13:1761–1770
    [Google Scholar]
  9. Diem K., Lentner C.editors 1975; Buffer solutions.. In Documenta Geigy Scientific Tables, 7th edn. pp 281–284 Macclesfield: Geigy Pharmaceuticals;
    [Google Scholar]
  10. Eras P., Goldstein M.J., Sherlock P. 1972; Candida infection of the gastrointestinal tract.. Medicine 51:367–379
    [Google Scholar]
  11. Guyton A.C. 1981; Digestion.. In Textbook of Medical Physiology, 6th edn. pp 801–815 Philadelphia: W. B. Saunders;
    [Google Scholar]
  12. Johnson E.M., Richardson M.D., Warnock D.W. 1984; In vitro resistance to imidazole anti- fungals in Candida albicans.. Journal of Antimicrobial Chemotherapy 13:547–558
    [Google Scholar]
  13. Kimura L.H., Pearsall N.N. 1978; Adherence of Candida albicans to human buccal epithelial cells.. Infection and Immunity 21:64–68
    [Google Scholar]
  14. King R.D., Lee J.C., Morris A.L. 1980; Adherence of Candida albicans and other Candida species to mucosal epithelial cells.. Infection and Immunity 27:667–674
    [Google Scholar]
  15. Lee J.C., King R.D. 1983; Characterisation of Candida albicans adherence to human vaginal epithelial cells in vitro.. Infection and Immunity 41:1024–1030
    [Google Scholar]
  16. Mathieson R., Dutta S.K. 1983; Candida oesophagitis.. Digestive Disease Science 28:365–369
    [Google Scholar]
  17. Myerowitz R.L. 1981; Gastrointestinal and disseminated candidiasis - an experimental model in the immunocompromised rat.. Archives of Pathology and Laboratory Medicine 105:138–143
    [Google Scholar]
  18. Persi M.A., Burnham J.C., Duhring J.L. 1985; Effects of carbon dioxide and pH on adhesion of Candida albicans to vaginal epithelial cells.. Infection and Immunity 50:82–90
    [Google Scholar]
  19. Rotrosen D., Calderone R.A., Edwards J.E.JR 1986; Adherence of Candida species to host tissues and plastic surfaces.. Reviews of Infectious Diseases 8:73–85
    [Google Scholar]
  20. Samaranayake L.P., Macfarlane T.W. 1982; Factors affecting the in vitro adherence of the fungal oral pathogen Candida albicans to epithelial cells of human origin.. Archives of Oral Biology 27:869–873
    [Google Scholar]
  21. Sandin R.L., Rogers A.L., Beneke E.S., Fernandez M.I. 1987a; Influence of mucosal cell origin on the in vitro adherence of Candida albicans: are mucosal cells from different sources equivalent?. Mycopathology 98:111–119
    [Google Scholar]
  22. Sandin R.L., Rogers A.L., Fernandez M.I., Beneke E.S. 1987b; Variations in affinity of Candida albicans in vitro among human buccal epithelial cells.. Journal of Medical Microbiology 27:151–155
    [Google Scholar]
  23. Segal E., Leher N., Ofek I. 1982; Adherence of Candida albicans to vaginal epithelial cells: inhibition of amino sugars.. Experimental Cell Biology 50:13–17
    [Google Scholar]
  24. Smith C.B. 1985; Candidiasis: pathogenesis, host resistance and predisposing factors.. In Candidiasis pp 53–70 Bodey G. P., Fainstein V. P. Edited by London: Raven Press;
    [Google Scholar]
  25. Smith K.J., Warnock D.W., Kennedy C.T.C., Johnson E.M., Hopwood V., Van Cutsem J., Vanden Bossche H. 1986; Azole resistance in Candida albicans.. Journal of Medical and Veterinary Mycology 24:133–144
    [Google Scholar]
  26. Sobel J.D., Myers P.G., Kaye D., Levison M.E. 1981; Adherence of Candida albicans to human vaginal and buccal epithelial cells.. Journal of Infectious Diseases 143:76–82
    [Google Scholar]
  27. Tavitian A., Raufman J., Rosenthal L.E., Weber J., Webber C.A., Dinesoy H.P. 1986; Ketoconazole-resistant Candida oesophagitis in patients with acquired immunodeficiency syndrome.. Gastroenterology 90:443–445
    [Google Scholar]
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