1887

Abstract

In iron-deficient conditions of growth ATCC 25416 excreted both pyochelin and a low-molecular-mass compound which strongly chelated iron(III), and facilitated iron translocation as demonstrated by growth and uptake experiments. The name cepabactin is proposed for this new siderophore. Comparisons of UV-visible spectra and chromatographic behaviour, together with H-NMR spectra, led to the conclusion that cepabactin is 1-hydroxy-5-methoxy-6-methyl-2(1H)-pyridinone, a compound which can be considered as a cyclic hydroxamate, but also as a heterocyclic analogue of catechol. This pyridinone has already been described by other workers as an antibiotic produced by , and by a soil isolate closely related to . Thus, cepabactin appears to act as a siderophore for more than one species of non-fluorescent pseudomonad.

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/content/journal/micro/10.1099/00221287-135-6-1479
1989-06-01
2019-09-23
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