%0 Journal Article %A Pietro, Rosemeire C. L. R. %A Jorge, João A. %A Terenzi, Héctor F. %T Pleiotropic Deficiency in the Control of Carbon-regulated Catabolic Enzymes in the ‘Slime’ Variant of Neurospora crassa %D 1989 %J Microbiology, %V 135 %N 5 %P 1375-1382 %@ 1465-2080 %R https://doi.org/10.1099/00221287-135-5-1375 %I Microbiology Society, %X A wall-less ‘slime’ strain of Neurospora crassa was shown to be pleiotropically altered in the production and secretion of several enzymes related to carbon catabolism, including invertase, alkaline protease, aryl-β-glucosidase and cellobiase. Invertase and protease were produced constitutively. The two β-glucosidases required induction by cellobiose but were poorly affected by glucose repression. Exoenzymes were released in larger amounts by the ‘slime’ strain than by the wild-type. Two other carbon-regulated enzymes, isocitrate lyase and phosphoenolpyruvate carboxykinase, were normally regulated in the ‘slime’ strain. A study of recombinants from a cross of a ‘slime’-containing heterokaryon and wild-type suggested that the anomalies observed were inherent in the ‘slime’ phenotype. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-135-5-1375