We have tested the hypothesis that the ciliary activity of epithelial cells from human nasal polyps is altered after infection with . Ciliated epithelial cells from human nasal polyps were cultured and infected with . The measurement of ciliary beating was based on a technique which enables one to monitor a fraction of a single ciliated cell. A marked decrease of ciliary beating frequency versus time was observed 24 h after infection with . About 50% of the cilia of infected cells were paralysed 48 h post-infection. The potential effect of infection on the physiological functions dependent on cilia is discussed.


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