1887

Abstract

A non-specific deoxyribonuclease with a possible role in the restriction of some actinophages was detected in ETHZ 22794. Production of this enzyme activity was influenced by the medium composition, indicating nutritional control of enzyme synthesis. Restriction was confirmed when phage adsorption and efficiency of plating in nuclease-productive and non-productive media were investigated, and also by analysis of a mutant which lacked exonucleolytic activity. escape from restriction in nuclease-productive media is mainly related to the ability of phages to adsorb in a growth phase earlier than that in which enzyme synthesis occurs.

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1988-08-01
2021-05-13
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References

  1. Braña A.F., Wolfe S., Demain A.L. 1985; Ammonium repression of cephalosporin production by Streptomyces clavuligerus. . Canadian Journal of Microbiology 31:736–743
    [Google Scholar]
  2. Chater K.F. 1978; Restriction in Streptomyces. . In Nocardia and Streptomyces; Proceedings of the International Symposium on Nocardia and Streptomyces pp 303–311 Mordarski M., Kurylowicz W., Jeljaszewicz J. Edited by Stuttgart & New York: Gustav Fischer Verlag;
    [Google Scholar]
  3. Chater K.F., Carter A.T. 1979; A new, wide host-range, temperate bacteriophage (R4) of Streptomyces and its interaction with some restriction- modification systems.. Journal of General Microbiology 115:431–442
    [Google Scholar]
  4. Chater K.F., Hopwood D.A. 1984; Streptomyces genetics.. In The Biology of the Actinomycetes pp 229–286 Goodfellow M., Mordarski M., Williams S. T. Edited by London: Academic Press;
    [Google Scholar]
  5. Chater K.F., Wilde L.C. 1976; Restriction of a bacteriophage of Streptomyces albus G involving endonuclease Sail. . Journal of Bacteriology 128:644–650
    [Google Scholar]
  6. Chater K.F., Hopwood D.A., Kieser T., Thompson C.J. 1982; Gene cloning in Streptomyces. . Current Topics in Microbiology and Immunology 96:69–95
    [Google Scholar]
  7. De Los Reyes-Gavilan C.G., Aparicio J.F., Barbes C., Hardisson C., Sanchez J. 1988; An exocytoplasmic endonuclease with restriction function in Streptomyces antibioticus. . Journal of Bacteriology 170:1339–1345
    [Google Scholar]
  8. Hardisson C., Manzanal M.B., Salas J.A., Suarez J.E. 1978; Fine structure, physiology and biochemistry of arthrospore germination in Streptomyces antibioticus. . Journal of General Microbiology 105:203–214
    [Google Scholar]
  9. Klaus S., Hartmann M., Krugel H., Roth M., Walter F., Rautenshtein Y.I., Solov’Eva N.Y. 1981; Restriction of Streptomyces phage SH5 by endonuclease Shyl from Streptomyces hygrosco- picus 0477.. Molecular and General Genetics 184:286–288
    [Google Scholar]
  10. Linn S.M. 1982; Nucleases involved in DNA repair.. In Nucleases pp 59–83 Linn S. M., Roberts R. J. Edited by Cold Spring Harbor, NY: Cold Spring Harbor Laboratory;
    [Google Scholar]
  11. Roberts R.J. 1984; Restriction and modification enzymes and their recognition sequences.. Nucleic Acids Research 12: Supplement rl67–r204
    [Google Scholar]
  12. Roganti F.S., Rosenthal A.L. 1983; DNAases of Acholeplasma spp.. Journal of Bacteriology 155:802–805
    [Google Scholar]
  13. Sanchez J., Barbes C., Hernandez A., De Los Reyes-Gavilan C.R.G., Hardisson C. 1985; Restriction-modification systems in Streptomyces antibioticus. . Canadian Journal of Microbiology 31:942–946
    [Google Scholar]
  14. Voeykova T.A., Ovekhov A.V., Rebentish B.A. 1980; New approaches to the study of restriction and modification systems in actinomycetes.. Actinomycetes 15:152–166
    [Google Scholar]
  15. Yanagida T., Ogawara H. 1980; Deoxyribonucleases in Streptomyces. . Journal of Antibiotics 33:1206–1207
    [Google Scholar]
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