1887

Abstract

has an inducible pathway which is responsible for the degradation of histidine. Induction of this pathway occurs in the presence of both glucose and ammonia. Growth yield experiments indicate that only two of the three available nitrogens are used for growth suggesting that formamide may be produced as a waste product. However, formamide was not detected in the culture fluid and formate was formed instead. These results suggest that histidine may be degraded in a novel pathway which results in the production of 1 mol each of ammonia, glutamate and formate per mol of histidine. The third nitrogen from histidine appears to be sequestered in some kind of secondary metabolite.

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/content/journal/micro/10.1099/00221287-134-8-2149
1988-08-01
2021-10-27
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References

  1. Brill W. J., Magasanik B. 1969; Genetic and metabolic control of histidinase and urocanase in Salmonella typhimurium,strain 15-59. Journal of Biological Chemistry 255:5392–5402
    [Google Scholar]
  2. Chasin L. A., Magasanik B. 1968; Induction and repression of the histidine degrading enzymes of Bacillus subtilis . Journal of Biological Chemistry 243:5165–5178
    [Google Scholar]
  3. Chiaverotti T. A., Parker G., Gallant J., Agabian N. 1981; Conditions which trigger guanosinetetraphosphate accumulation in Caulobacter crescentus . Journal of Bacteriology 145:1463–1465
    [Google Scholar]
  4. Coote J. G., Hassall H. 1973a; The degradation of l-histidine, imadazolyl-l-lactate and imidazolyl-propionate by Pseudomonas testosteroni . Biochemical Journal 132:404–422
    [Google Scholar]
  5. Coote J. G., Hassall H. 1973b; The control of the enzymes degrading histidine and related imidazolyl derivatives in Pseudomonas testosteroni . Biochemical Journal 132:423–433
    [Google Scholar]
  6. Davis R. W., Botstein D. N., Roth J. R. 1980 A Manual for Genetic Engineering: Advanced Bacterial Genetics. Cold Spring Harbor, NY:: Cold Spring Harbor Laboratory.;
    [Google Scholar]
  7. Ely B., Amarasinghe A. B. C., Bender R. A. 1978; Ammonia assimilation and glutamate formation in Caulobacter crescentus . Journal of Bacteriology 133:225–230
    [Google Scholar]
  8. Ferber D. M., Ely B. 1982; Resistance of amino acid inhibition in Caulobacter crescentus . Molecular and General Genetics 187:446–452
    [Google Scholar]
  9. Johnson R. C., Ely B. 1977; Isolation and spontaneously-derived mutants from Caulobacter crescentus . Genetics 86:25–32
    [Google Scholar]
  10. Kurn N., Shapiro L., Agabian N. 1977; Effect of carbon source and the role of cyclic adenosine 3′,5′-monophosphate on the Caulobacter cell cycle. Journal of Bacteriology 131:951–959
    [Google Scholar]
  11. Lang E., Lang H. 1972; Specific colour reaction for the direct identification of formic acid. Zeitschrift für Analytische Chemie 160:8–10
    [Google Scholar]
  12. Leidgh B. J., Wheelis M. L. 1973; Genetic control of the histidinedissimilatory pathway in Pseudomonas putida . Molecular and General Genetics 120:201–210
    [Google Scholar]
  13. Lessie T. G., Neidhardt F. C. 1967; Formation and operation of the histidine-degrading pathway in Pseudomonas aeruginosa . Journal of Bacteriology 93:1800–1810
    [Google Scholar]
  14. Lund P., Magasanik B. 1965; N-Formimino-l-glutamate formiminohydrolase of Aerobacter aerogenes . Journal of Biological Chemistry 140:43l6–4319
    [Google Scholar]
  15. Magasanik B. 1982; Genetic control of nitrogen assimilation. Annual Review of Genetics 16:135–168
    [Google Scholar]
  16. Magasanik B., Bowser H. R. 1955; The degradation of histidine by Aerobacter aerogenes . Journal of Biological Chemistry 213:571–580
    [Google Scholar]
  17. Meiss H. K., Brill W. J., Magasanik B. 1969; Genetic control of histidine degradation in Salmonella typhimurium, strain Lt-2. Journal of Biological Chemistry 244:5382–5391
    [Google Scholar]
  18. Poindexter J. S. 1964; Biological properties and classification of the Caulobacter group. Bacteriological Reviews 28:231–295
    [Google Scholar]
  19. Schlesinger S., Scotto P., Magasanik B. 1965; Exogenous and endogenous induction of the histidine-degrading enzymes in Aerobacter aerogenes . Journal of Biological Chemistry 240:4331–4337
    [Google Scholar]
  20. Smith G. R., Magasanik B. 1971; Nature and selfregulated synthesis of the repression of the hut operons in Salmonella typhimurium . Proceedings of the National Academy of Sciences of the United States of America 68:1493–1497
    [Google Scholar]
  21. Smith G. R., Halpern Y. S., Magasanik B. 1971; Genetic and metabolic control of enzymes responsible for histidine degradation in Salmonella typhimurium . Journal of Biological Chemistry 246:3320–3329
    [Google Scholar]
  22. Tabor H. 1955; Degradation of histidine. In A Symposium on Amino Acid Metabolism pp. 373–390 Mcelroy W. D., Glass H. B. Edited by Baltimore: Johns Hopkins Press;
    [Google Scholar]
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