Summary: The chemical and serological characteristics of lipopolysaccharides (LPS) isolated from bio-serogroup 1875 were compared with those of O1 LPS. bio-serogroup 1875 LPS contained all the component sugars which were found in O1 LPS, i.e. glucose, L-glycero-D-manno-heptose, fructose, glucosamine, perosamine and quinovosamine, though the amount of perosamine, a characteristic component of O1 LPS, was very low compared with that of O1 LPS. Their LPS additionally contained mannose and two unidentified neutral sugars which are not regular constituents of O1 V. cholerae LPS. Definite serological cross-reactivity in the passive haemolysis test between LPS from bio-serogroup 1875 and LPS from O1 was demonstrated.


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