Effect of Dilution Rate and Mg Limitation on Toxic Shock Syndrome Toxin-1 Production by Grown in Defined Continuous Culture Free

Abstract

A toxic shock syndrome isolate of was grown in a chemostat, in a defined synthetic medium of six amino acids, glucose, two vitamins and salts. Steady states were achieved under limiting and replete Mg conditions and at a range of relative specific growth rates. The biomass and toxic shock syndrome toxin-1 (TSST-1) were estimated at each condition. Under Mg limitation the biomass and TSST-1 production rates were reduced compared to Mg replete conditions. Optimal TSST-1 production occurred at 0.81 relative specific growth rate.

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1988-03-01
2024-03-29
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