SUMMARY: The gene encoding pilin of 340 has been isolated and the nucleotide sequence determined. The gene is present as a single copy within the genome and a protein of 16683 can be predicted from the proposed coding region. A comparison of the predicted amino acid sequence with pilin from other strains of indicated that the protein of strain 340 (serogroup D) has a high degree of similarity with pilin of strain 265 (serogroup H). The degree of similarity between pilins from these strains and from other serogroups is no greater than that between pilins and the homologous proteins of several different bacterial species. These findings suggest that serogroups D and H may form a subset of serogroups.


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