%0 Journal Article %A Pažout, Jaroslav %A Schröder, Peter %T Microcycle Conidiation in Submerged Cultures of Penicillium cyclopium Attained without Temperature Changes %D 1988 %J Microbiology, %V 134 %N 10 %P 2685-2692 %@ 1465-2080 %R https://doi.org/10.1099/00221287-134-10-2685 %I Microbiology Society, %X Microcycle conidiation in shaken cultures of Penicillium cyclopium M 79 was induced at 24°C without any shock treatment. The occurrence of a microcycle depended on the presence of an organic acid (especially glutamic acid) in combination with glucose, low phosphate concentration, light and sufficient aeration. Absence of glucose and/or lowered aeration evoked vegetative growth. A synchronous and homogeneous microcycle required a certain relationship between the number of inoculated conidia and the concentration of the organic acid in the medium; the optimum was at 0·08 nmol acid per conidium. Higher values stimulated normal vegetative growth. A shortage or absence of the organic acid led to an atypical growth. The effect of organic acid can be partially replaced by addition of 2% (w/v) CaCO3. Addition of NH+ 4 in concentrations higher than 6 mm to cultures with glutamate or glutamine evoked vegetative growth. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-134-10-2685