@article{mbs:/content/journal/micro/10.1099/00221287-134-10-2685, author = "Pažout, Jaroslav and Schröder, Peter", title = "Microcycle Conidiation in Submerged Cultures of Penicillium cyclopium Attained without Temperature Changes", journal= "Microbiology", year = "1988", volume = "134", number = "10", pages = "2685-2692", doi = "https://doi.org/10.1099/00221287-134-10-2685", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-134-10-2685", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "Microcycle conidiation in shaken cultures of Penicillium cyclopium M 79 was induced at 24°C without any shock treatment. The occurrence of a microcycle depended on the presence of an organic acid (especially glutamic acid) in combination with glucose, low phosphate concentration, light and sufficient aeration. Absence of glucose and/or lowered aeration evoked vegetative growth. A synchronous and homogeneous microcycle required a certain relationship between the number of inoculated conidia and the concentration of the organic acid in the medium; the optimum was at 0·08 nmol acid per conidium. Higher values stimulated normal vegetative growth. A shortage or absence of the organic acid led to an atypical growth. The effect of organic acid can be partially replaced by addition of 2% (w/v) CaCO3. Addition of NH+ 4 in concentrations higher than 6 mm to cultures with glutamate or glutamine evoked vegetative growth.", }