1887

Abstract

SUMMARY: The amino-terminal end of the 168 kDa adherence protein from the membrane of was sequenced up to 12 amino acids. A synthetic peptide containing nine amino acids of this sequence was used to study the antigenicity of the amino-terminus of the 168 kDa protein and the involvement of the homologous sequence of the protein in the adherence process. The synthetic peptide when coupled to ovalbumin was immunogenic in rabbits. Antibodies against this peptide epitope could be demonstrated in sera taken during natural infection in humans. The structural domain of the 168 kDa protein homologous with the synthetic peptide did not appear to be involved in adherence, as the synthetic peptide or its homologous antibody failed to inhibit adherence of

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-133-8-2233
1987-08-01
2024-12-12
Loading full text...

Full text loading...

/content/journal/micro/10.1099/00221287-133-8-2233
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error