RT Journal Article SR Electronic(1) A1 Quain, David E. A1 Boulton, Christopher A.YR 1987 T1 Growth and Metabolism of Mannitol by Strains of Saccharomyces cerevisiae JF Microbiology, VO 133 IS 7 SP 1675 OP 1684 DO https://doi.org/10.1099/00221287-133-7-1675 PB Microbiology Society, SN 1465-2080, AB SUMMARY: Of 40 polyploid strains of Saccharomyces cerevisiae screened for growth on D-mannitol (5%, w/v), half grew well (5-20 mg dry biomass ml−1). Certain of these strains were unable to grow on low concentrations of mannitol (1-2%, w/v) and others, initially unable to grow on mannitol, exhibited long-term adaptation to growth. An NAD+-dependent D-mannitol dehydrogenase (EC 1.1.1.67) was detected in mannitol-grown yeast. Growth was dependent on mitochondrial function and was obligately aerobic. Measurement of products of metabolism and respiratory activity indicated that growth on mannitol allows catabolite derepression., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-133-7-1675