1887

Abstract

SUMMARY: During development of the homothallic ascomycete , asexual sporulation is followed by sexual sporulation. We report here the detection of a solvent-extractable activity which inhibits asexual sporulation and stimulates premature sexual sporulation. This activity, called precocious sexual inducer (psi), is overproduced by certain mutants that are blocked in both modes of sporulation. Using partially purified preparations of psi, biological response could be elicited with as little as 50 ng of material. We suggest that psi is a hormone-precursor which is converted to a hormone by normal sporulating strains that respond to psi, but not by the asporogenous mutants that overproduce psi. The stability of psi activity gives promise that the compound can be purified and identified.

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/content/journal/micro/10.1099/00221287-133-5-1383
1987-05-01
2021-10-18
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References

  1. Ballantine J. A., Ferrito V., Hassall C. H. 1971; The biosynthesis of asperugin in Aspergillus rugulosus. Phytochemistry 10:1309–1313
    [Google Scholar]
  2. Butnick N. Z., Yager L. N., Hermann T. E., Kurtz M. B., Champe S. P. 1984a; Mutants of Aspergillus nidulans blocked at an early stage of sporulation secrete an unusual metabolite. Journal of Bacteriology 160:533–540
    [Google Scholar]
  3. Butnick N. Z., Yager L. N., Kurtz M. B., Champe S. P. 1984b; Genetic analysis of mutants of Aspergillus nidulans blocked at an early stage of sporulation. Journal of Bacteriology 160:541–545
    [Google Scholar]
  4. Gooday G. W. 1983; Fungal hormones. In Secondary Metabolism and Differentiation in Fungi pp. 239–266 Bennett J. W., Ciegler A. Edited by New York: Marcel Dekker;
    [Google Scholar]
  5. Hermann T. E., Kurtz M. B., Champe S. P. 1983; Laccase localized in hulle cells and cleistothecial primordia of Aspergillus nidulans. Journal of Bacteriology 154:955–964
    [Google Scholar]
  6. Kafer E. 1965; Origins of translocations in Aspergillus nidulans. Genetics 52:217–232
    [Google Scholar]
  7. Kurtz M. B., Champe S. P. 1981; Dominant spore color mutants of Aspergillus nidulans defective in germination and sexual development. Journal of Bacteriology 148:629–638
    [Google Scholar]
  8. Serlupi-Crescenzi O., Kurtz M. B., Champe S. P. 1983; Developmental defects resulting from arginine auxotrophy in Aspergillus nidulans. Journal of General Microbiology 129:3535–3544
    [Google Scholar]
  9. Timberlake W. E. 1980; Developmental gene regulation in Aspergillus nidulans. Developmental Biology 78:497–510
    [Google Scholar]
  10. Yager L. N., Kurtz M. B., Champe S. P. 1982; Temperature-shift analysis of conidial development in Aspergillus nidulans. Developmental Biology 93:92–103
    [Google Scholar]
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