@article{mbs:/content/journal/micro/10.1099/00221287-133-2-445, author = "Rutgers, M. and Teixeira De Mattos, M. J. and Postma, P. W. and Van Dam, K.", title = "Establishment of the Steady State in Glucose-limited Chemostat Cultures of Klebsiella pneumoniae", journal= "Microbiology", year = "1987", volume = "133", number = "2", pages = "445-451", doi = "https://doi.org/10.1099/00221287-133-2-445", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-133-2-445", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "To investigate the relationship between growth rate and concentration of the nutrient that limits growth, ‘Klebsiella aerogenes’ NCTC 418 (K. pneumoniae) was grown in a glucose-limited chemostat. The actual time required to establish a steady-state glucose concentration exceeded that expected theoretically. Apparently, there is a long-term adaptation of the cells to nutrient limitation. As yet, it is not clear whether this has a phenotypic or genetic origin. In the final steady state, the dependence of the growth rate on glucose concentration could be mathematically described equally well by a hyperbolic and by a logarithmic function.", }