RT Journal Article SR Electronic(1) A1 Mcclure, Nicholas C. A1 Venables, W. A.YR 1986 T1 Adaptation of Pseudomonas putida mt-2 to Growth on Aromatic Amines JF Microbiology, VO 132 IS 8 SP 2209 OP 2218 DO https://doi.org/10.1099/00221287-132-8-2209 PB Microbiology Society, SN 1465-2080, AB Summary: Pseudomonas putida mt-2 (ATCC 33015) carrying the TOL plasmid pWW0 could adapt to growth on the aromatic amines aniline and m-and p-toluidine. In strain UCC2, a derivative adapted to rapid growth on these compounds, they were oxidatively deaminated to catechol or 4-methylcatechol, which in turn were dissimilated by a meta-cleavage pathway. The aniline/toluidine oxygenase and the meta-cleavage pathway enzymes were inducible by aromatic amines. Evidence is presented that in strain UCC2, plasmid pWWO has undergone deletion of its catabolic genes, and that it is a novel plasmid, pTDNl, which is involved in the catabolism of aniline and m-and p-toluidine. The meta-cleavage pathway genes which are carried by pTDN 1 were shown not to have originated in pWW0., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-132-8-2209