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Summary: Ten informational nuclear suppressors of the oxil
− mitochondrial mutation of Saccharomyces cerevisiae are recessive. They are linked to each other, but their allelism is uncertain. Some of them unfavourably affect functions of standard (mit
+) mitochondrial genomes. One suppressor severely impairs or entirely prevents mitochondrial functions of the spore clones carrying it. The spectrum of mit
− mutations on which these suppressors act is similar to that exhibited by nam3-l. In double heterozygotes nam
x/NAM3+,
nam3-l the oxil
− (and box3-) mutation is suppressed, yet one of our suppressors (R705) and nam3-l show independent segregation in tetrads. This indicates that there may be absence of complementation between non-allelic suppressors.
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