RT Journal Article SR Electronic(1) A1 CRAMERI, RETO A1 DAVIES, JULIAN E. A1 HÜTTER, RALFYR 1986 T1 Plasmid Curing and Generation of Mutations Induced with Ethidium Bromide in Streptomycetes JF Microbiology, VO 132 IS 3 SP 819 OP 824 DO https://doi.org/10.1099/00221287-132-3-819 PB Microbiology Society, SN 1465-2080, AB SUMMARY: The DNA-intercalating agent ethidium bromide was used to eliminate plasmid DNA from streptomycetes. Other mutational events associated with chromosome changes occurred at high frequency; they resulted in phenotypic changes such as loss of enzyme activity, antibiotic resistance or ability to sporulate., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-132-3-819