1887

Abstract

SUMMARY: The DNA-intercalating agent ethidium bromide was used to eliminate plasmid DNA from streptomycetes. Other mutational events associated with chromosome changes occurred at high frequency; they resulted in phenotypic changes such as loss of enzyme activity, antibiotic resistance or ability to sporulate.

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1986-03-01
2024-04-25
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References

  1. Ahmed Z. U., Vining L. C. 1983; Evidence for a chromosomal location of the genes coding for chloramphenicol production in Streptomyces vene-zuelae. Journal of Bacteriology 154:239–244
    [Google Scholar]
  2. Akagawa H., Okanishi M., Umezawa H. 1975; A plasmid involved in chloramphenicol production in Streptomyces venezuelae: evidence from genetic mapping. Journal of General Microbiology 90:336–356
    [Google Scholar]
  3. Akagawa H., Okanishi M., Umezawa H. 1979; Genetic and biochemical studies of chloramphenicol non-producing mutants of Streptomyces venezuelae carrying plasmids. Journal of Antibiotics 32:610–620
    [Google Scholar]
  4. Altenbuchner j., Cullum J. 1984; DNA amplification and unstable arginine gene in Streptomyces lividans 66. Molecular and General Genetics 195:134–138
    [Google Scholar]
  5. Crameri R., Kieser T., Ono H., Sanchez J., Hutter R. 1983; Chromosomal instability in Streptomyces glaucescens: mapping of streptomycinsensitive mutants. Journal of General Microbiology 129:519–527
    [Google Scholar]
  6. Crameri R., Hintermann G., Hutter R., Kieser T. 1984; Tyrosinase activity in Streptomyces glaucescens is controlled by three chromosomal loci. Canadian Journal of Microbiology 30:1058–1067
    [Google Scholar]
  7. Freeman R. F., Hopwood D. A. 1978; Unstable naturally occurring resistance to antibiotics in Streptomyces. Journal of General Microbiology 106:377–381
    [Google Scholar]
  8. Friend E. J., Warren M., Hopwood D. A. 1978; Genetic evidence for a plasmid controlling fertility in an industrial strain of Streptomyces rimosus. Journal of General Microbiology 106:201–206
    [Google Scholar]
  9. Gregory K.F., Huang J. C. C. 1964a; Tyrosinase inheritance of Streptomyces scabies. I. Genetic recombination. Journal of Bacteriology 87:1281–1286
    [Google Scholar]
  10. Gregory K. F., Huang J. C. C. 1964b; Tyrosinase inheritance in Streptomyces scabies. II. Induction of tyrosinase deficiency by acridine dyes. Journal of Bacteriology 87:1287–1294
    [Google Scholar]
  11. Gregory K. F., Shyu W. J. 1961; Apparent cytoplasmatic inheritance of tyrosinase competence in Streptomyces scabies. Nature, London 191:465–467
    [Google Scholar]
  12. Hintermann G., Hütter R. 1984; Structural and functional characterization of two unstable genes of Streptomyces glaucescens. Proceedings of the ASM conference on genetics and molecular biology of industrial microorganisms Bloomington, Indiana, abstract no 216, pp309–310
    [Google Scholar]
  13. Hintermann G., Crameri R., Vögtli M., Hütter R. 1984; Streptomycin sensitivity by Streptomyces glaucescens is due to deletions comprising the structural gene coding for a specific phosphotransferase. Molecular and General Genetics 196:513–520
    [Google Scholar]
  14. Hopwood D. A. 1978; Extrachromosomally determined antibiotic production. Annual Review of Microbiology 32:373–392
    [Google Scholar]
  15. Hopwood D. A., Merrick M. J. 1977; Genetics of antibiotic production. Bacteriological Reviews 41:595–635
    [Google Scholar]
  16. Hopwood D. A., Bibb M. J., Bruton C. J., Chater K. F., Feitelson J. S., Gil J. A. 1983; Cloning Streptomyces genes for antibiotic production. Trends in Biotechnology 1:42–48
    [Google Scholar]
  17. Hütter R., Kieser T., Crameri R., Hintermann G. 1981; Chromosomal instability in Streptomyces glaucescens. Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene (supplement) 11:551–559
    [Google Scholar]
  18. Katz E., Thompson C. J., Hopwood D. A. 1983; Cloning and expression of the tyrosinase gene from Streptomyces antibioticus in Streptomyces lividans. Journal of General Microbiology 129:2703–2714
    [Google Scholar]
  19. Kieser T. 1984; Factors affecting the isolation of cccDNA from Streptomyces lividans and Escherichia coli. Plasmid 12:19–36
    [Google Scholar]
  20. Kieser T., Hopwood D. A., Wright H. M., Thompson C. J. 1982; pIJ101, a multi-copy broad host-range Streptomyces plasmid: functional analysis and development of DNA cloning vectors. Molecular and General Genetics 185:223–238
    [Google Scholar]
  21. Komatsu K., Leboul J., Harford S., Davies J. 1981; Studies of plasmids in neomycin-producing Streptomyces fradiae. Edited by D. Schlessinger. Washington, DC: American Society for Microbiology. In Microbiology 1981, pp334–337
    [Google Scholar]
  22. Lomovskaya N. D., Mkrtumian N. M., Gostims-KAYA N. L., Danilenko V. N. 1972; Characterization of temperate actinophage C31 isolated from Streptomyces coelicolor A3(2). Journal of Virology 9:248–252
    [Google Scholar]
  23. Malik V. S. 1977; Preparative method for the isolation of supercoiled DNA from a chloramphenicol-producing streptomycete. Journal of Antibiotics 30:897–899
    [Google Scholar]
  24. Malik V. S. 1980; Plasmid and chloramphenicol production in Streptomyces venezuelae. Biotechnology Letters 2:455–457
    [Google Scholar]
  25. Michelson A. M., Vining L. C. 1978; Loss of chloramphenicol production in strains of Streptomyces species 3022a treated with acriflavine and ethidium bromide. Canadian Journal of Microbiology 24:662–669
    [Google Scholar]
  26. Okanishi M., Umezawa H. 1978; Plasmids involved in antibiotic production in streptomvcetes. Edited by E. Freerksen, I. Tarnok & J. ri. Thumin. Stuttgart & New York: Gustav Fischer Verlag. In Genetics of the Actinomyceteales, pp19–38
    [Google Scholar]
  27. Okanishi M., Ohta T., Umezawa H. 1970; Possible control of aerial mycelium formation and antibiotic production in Streptomyces by episomic factors. Journal of Antibiotics 23:45–47
    [Google Scholar]
  28. Ono H., Crameri R., Hintermann G., Hutter R. 1983; Hydroxystreptomycin production and resistance in Streptomyces glaucescens. Journal of General Microbiology 129:529–537
    [Google Scholar]
  29. Pogell B. M. 1979; Regulation of aerial mycelium formation in streptomycetes. Edited by O. K. Sebek & A. J. Laskin. Washington, DC: American Society for Microbiology. In Proceeding of the 3rd International Symposium on Genetics of Industrial Microorganisms, pp218–224
    [Google Scholar]
  30. Pridham T. G., Anderson P., Foley C., Lindens-felder L. A., Benedict L. A. 1956/7; A selection of media for maintenance and taxonomic study of Streptomyces. Antibiotics Annual947–953
    [Google Scholar]
  31. Schrempf H. 1981; Functional aspects of streptomycete plasmids. Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene (supplement) 11:545–550
    [Google Scholar]
  32. Schrempf H. 1983; Deletion and amplification of DNA sequences in melanin-negative variants of Streptomyces reticuli. Molecular and General Genetics 189:501–505
    [Google Scholar]
  33. Schrempf H., Goebel W. 1979; Function of plasmid genes in Streptomyces reticuli. Edited by K. N. Timmis & A. Piihler. Amsterdam: Elsevier/North-Holland. In Plasmids of Medical, Environmental and Commercial Importance, pp259–268
    [Google Scholar]
  34. Shaw P. D., Piwowarski J. 1977; Effect of ethidium bromide and acriflavine on streptomycin-production by Streptomyces bikiniensis. Journal of Antibiotics 30:404–408
    [Google Scholar]
  35. Suter A. M. 1978; Isolierung und Charakterisierung von Melanin-negativen Mutanten aus Streptomyces glaucescens. Thesis no. 6276, Eidgenössische Technische Hochschule Zürich, Switzerland.
    [Google Scholar]
  36. Thompson C. J., Ward J., Hopwood D. A. 1982a; Cloning of antibiotic resistance and nutritional genes in streptomycetes. Journal of Bacteriology 151:668–677
    [Google Scholar]
  37. Thompson C. J., Kieser T., Ward J. M., Hopwood D. A. 1982b; Physical analysis of antibiotic resistance genes from Streptomyces and their use in vector construction. Gene 20:51–62
    [Google Scholar]
  38. Vivian A. 1971; Genetic control of fertility in Streptomyces coelicolor A3(2): plasmid involvement in the interconversion of UF and IF strains. Journal of General Microbiology 69:353–364
    [Google Scholar]
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