%0 Journal Article %A Wolf, Marcia K. %A Crosa, Jorge H. %T Evidence for the Role of a Siderophore in Promoting Vibrio anguillarum Infections %D 1986 %J Microbiology, %V 132 %N 10 %P 2949-2952 %@ 1465-2080 %R https://doi.org/10.1099/00221287-132-10-2949 %I Microbiology Society, %X SUMMARY: Vibrio anguillarum strain 775 harbouring the virulence plasmid pJM1 produces a plasmid-mediated siderophore that can crossfeed siderophore-deficient, receptor-proficient mutants of V. anguillarum in vitro. Experimental infections of salmonid fishes with mixtures consisting of the wild-type strain and a siderophore-deficient, receptor-proficient mutant resulted in recovery of both the wild-type and the mutant strain, while in infections with mixtures consisting of the wild-type strain and a siderophore-deficient, receptor-deficient mutant only the wild-type strain could be recovered. These results suggest that the V. anguillarum plasmid-mediated siderophore is produced in vivo in a diffusible form and that it is an important factor of virulence. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-132-10-2949