1887

Abstract

SUMMARY: The effects of thioglycerol on growth and aflatoxin production by were studied using conidia-initiated cultures and pregrown mycelia. Thioglycerol inhibited both growth and aflatoxin synthesis, with toxin formation being affected to a greater extent. This inhibitory activity could not be overcome by addition of methionine or zinc sulphate. Accompanying respirometric studies suggested that the primary mode of action of thioglycerol involves an inhibition of oxygen utilization.

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/content/journal/micro/10.1099/00221287-132-10-2767
1986-10-01
2021-05-06
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References

  1. Abdollahi A., Buchanan R. L. 1981; Regulation of aflatoxin biosynthesis: induction of aflatoxin production by various carbohydrates. Journal of Food Science 46:633–635
    [Google Scholar]
  2. Buchanan R. L., Ayres J. C. 1977; Effect of various glycolytic and TCA cycle intermediates on aflatoxin production. Journal of Food Safety 1:19–28
    [Google Scholar]
  3. Buchanan R. L., Houston W. M. 1982; Production of blue-fluorescent pyrazines by Aspergillus parasiticus. Journal of Food Science 47:779–782
    [Google Scholar]
  4. Buchanan R. L., Lewis D. F. 1984a; Caffeine inhibition of aflatoxin synthesis: probable site of action. Applied and Environmental Microbiology 47:1216–1220
    [Google Scholar]
  5. Buchanan R. L., Lewis D. F. 1984b; Regulation of aflatoxin biosynthesis: effect of glucose on the activities of various glycolytic enzymes. Applied and Environmental Microbiology 48:306–310
    [Google Scholar]
  6. Buchanan R. L., Stahl H. G. 1984; Ability of various carbon sources to induce and support aflatoxin synthesis by Aspergillus parasiticus. Journal of Food Safety 6:271–279
    [Google Scholar]
  7. Buchanan R. L., Hoover D. G., Jones S. B. 1983; Caffeine inhibition of aflatoxin production: mode of action. Applied and Environmental Microbiology 46:1193–1200
    [Google Scholar]
  8. Buchanan R. L., Federowicz D., Stahl H. G. 1985a; Activities of tricarboxylic acid cycle enzymes in an aflatoxigenic strain of Aspergillus parasiticus after a peptone to glucose carbon source shift. Transactions of the British Mycological Society 84:267–275
    [Google Scholar]
  9. Buchanan R. L., Ocher L. A., Stahl H. G. 1985b; Effect of 2-deoxyglucose, α-methylglucoside, and glucosamine on aflatoxin production by Aspergillus parasiticus. Archives of Microbiology 142:200–203
    [Google Scholar]
  10. Clevstrom G., Ljunggren H., Tegelströ S., Tideman K. 1983; Production of aflatoxin by an Aspergillus flavus isolate cultured under a limited oxygen supply. Applied and Environmental Microbiology 46:400–405
    [Google Scholar]
  11. Davis N. D., Diener U. L. 1968; Growth and aflatoxin production by Aspergillus parasiticus from various carbon sources. Applied Microbiology 16:158–159
    [Google Scholar]
  12. Davis N. D., Diener U. L., Eldridge D. W. 1966; Production of aflatoxins B1 and G1 in a semisynthetic medium. Applied Microbiology 14:378–380
    [Google Scholar]
  13. Gupta S. K., Maggon K. K., Venkitasubramanian T. A. 1976; Inhibition of aflatoxin formation by 2-mercaptoethanol. Applied and Environmental Microbiology 32:324–326
    [Google Scholar]
  14. Javor G. T. 1983a; Depression of adenosylmethionine content of Escherichia coli by thioglycerol. Antimicrobial Agents and Chemotherapy 24:860–867
    [Google Scholar]
  15. Javor G. T. 1983b; Inhibition of respiration of Escherichia coli by thioglycerol. Antimicrobial Agents and Chemotherapy 24:868–870
    [Google Scholar]
  16. Jensen K. K., Javor G. T. 1981; Inhibition of Escherichia coli by thioglycerol. Antimicrobial Agents and Chemotherapy 19:556–561
    [Google Scholar]
  17. Mateles R. I., Adye J. C. 1965; Production of aflatoxins in submerged cultures. Applied Microbiology 13:208–211
    [Google Scholar]
  18. Tice G., Buchanan R. L. 1982; Regulation of aflatoxin biosynthesis; effect of exogenously-supplied cyclic nucleotides. Journal of Food Science 47:153–157
    [Google Scholar]
  19. Wilson D. M., Huang L. H., Jay E. 1975; Survival of Aspergillus flavus and Fusarium moniliforme in high-moisture corn stored under modified atmospheres. Applied Microbiology 30:592–595
    [Google Scholar]
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