1887

Abstract

Summary: Puromycin is a potent inhibitor of bacterial protein synthesis, but puromycin-producing KCC S-0309 is tolerant to the antibiotic Puromycin bound to both 30S and 50S ribosomal subunits from and inhibited polyuridylate-directed polyphenylalanine synthesis by the ribosomes. However, the organism possessed a novel puromycin-inactivating enzyme which acetylated the antibiotic at the 2″-NH group of the -methyltyrosine moiety.

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/content/journal/micro/10.1099/00221287-131-8-1999
1985-08-01
2019-11-19
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-131-8-1999
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