Biochemical Basis of Resistance to Hygromycin B in Streptomyces hygroscopicus – the Producing Organism

References

1. Benveniste R., Davies J. 1973; Aminoglycoside antibiotic-inactivating enzymes in Actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria. Proceedings of the National Academy of Sciences of the United States of America 702276–2280
   [Google Scholar]
2. Bradford M. M. 1976; A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72:248–254
   [Google Scholar]
3. Cabañas M. J., Vazquez D., Modolell J. 1978; Dual interference of hygromycin B with ribosomal translocation and with aminoacyl-tRNA recognition. European Journal of Biochemistry 87:21–27
   [Google Scholar]
4. Chater K. F., Hopwood D. A., Kieser T., Thompson C. J. 1982; Gene cloning in Streptomyces. Current Topics in Microbiology and Immunology 96:69–95
   [Google Scholar]
5. Goldman P. R., Northrop D. B. 1976; Purification and spectrophotometric assay of neomycin phosphotransferase. II. Biochemical and Biophysical Research Communications 69:230–236
   [Google Scholar]
6. Gonzalez A., Jimenez A., Vazquez D., Davies J. E., Schindler D. 1978; Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes. Biochimica et biophysica acta 521:459–469
   [Google Scholar]
7. Gritz L., Davies J. 1983; Plasmid-encoded hygromycin B resistance : the sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae . Gene 25:179–188
   [Google Scholar]
8. Haas M. J., Dowding J. E. 1975; Aminoglyco-side-modifying enzymes. Methods in Enzymology 43:611–628
   [Google Scholar]
9. Herbert C. J., Giles I. G., Akhtar M. 1983; The sequence of an antibiotic resistance gene from an antibiotic producing bacterium. FEBS Letters 160:67–71
   [Google Scholar]
10. Raster K. R., Burgett S. G., Rao R. N., Ingolla T. D. 1983; Analysis of a bacterial hygromycin B resistance gene by transcriptional and translational fusions and DNA sequencing. Nucleic Acids Research 11:6895–6911
    [Google Scholar]
11. Leboul J., Davies J. 1982; Enzymatic modification of hygromycin B in Streptomyces hygroscopicus . Journal of Antibiotics 35:527–528
    [Google Scholar]
12. Malpartida F., Zalacain M., Jimenez J., Davies J. 1983; Molecular cloning and expression in Streptomyces lividans of a hygromycin B phosphotransferase gene from Streptomyces hygroscopicus . Biochemical and Biophysical Research Communications 117:6–12
    [Google Scholar]
13. Mikulik K., Jiranova A., Weiser J., Janda I., Stastna J., Quyen N. 1983; Translation of poly(U) on ribosomes from Streptomyces aureofaciens . Biochimica et biophysica acta 740:99–107
    [Google Scholar]
14. Miller J. H. 1972 Experiments in Molecular Genetics Cold Spring Harbor, NY: Cold Spring Harbor Laboratory;
    [Google Scholar]
15. Perez-Gonzalez J. A., Vara J., Jimenez A. 1983; Acetylation of puromycin by Streptomyces alboniger the producing organism. Biochemical and Biophysical Research Communications 113:772–777
    [Google Scholar]
16. Rao R. N., Allen N. E., Hobbs J. N., Alborn W. E., Kirst H. A., Paschal J. W. 1983; Genetic and enzymatic basis of hygromycin B resistance in Escherichia coli . Antimicrobial Agents and Chemotherapy 24:689–695
    [Google Scholar]
17. Sanchez L., Vazquez D., Jimenez A. 1977; Genetics and biochemistry of cryptopleurine resistance in the yeast Saccharomyces cerevisiae . Molecular and General Genetics 156:319–326
    [Google Scholar]
18. Singh A., Ursic D., Davies J. 1979; Phenotypic suppression and misreading in Saccharomyces cerevisiae . Nature London: 277146–148
    [Google Scholar]
19. Skinner R. H., Cundliffe E. 1980; Resistance to the antibiotics viomycin and capreomycin in the Streptomyces species which produce them. Journal of General Microbiology 120:95–104
    [Google Scholar]
20. Sugiyama M., Nimi O., Nomi R. 1980; Susceptibility of protein synthesis to neomycin in neomycin-producing Streptomyces fradiae . Journal of General Microbiology 121:477–478
    [Google Scholar]
21. Thompson C. J., Gray G. S. 1983; Nucleotide sequence of a Streptomycete aminoglycoside phos-photransferase gene and its relationship to phospho-transferases encoded by resistance plasmids. Proceedings of the National Academy of Sciences of the United States of America 80:5190–5194
    [Google Scholar]
22. Thompson C. J., Ward J. M., Hopwood D. 1980; DNA cloning in Streptomyces: resistance genes from antibiotic-producing species. Nature London: 286:525–527
    [Google Scholar]
23. Thompson C. J., Skinner R. H., Thompson J., Ward J. M., Hopwood D., Cundliffe E. 1982; Biochemical characterization of resistance determinants cloned from antibiotic-producing Streptomycetes . Journal of Bacteriology 151:678–685
    [Google Scholar]
24. Umezawa H., Kondo S. 1982 Mechanisms of Resistance to Aminoglycoside Antibiotics267–292 Umezawa M., Hooper I. R. Berlin, Heidelberg, New York: Springer-Verlag;
    [Google Scholar]
25. Umezawa H., Okanishi M., Utahara R., Maeda K., Kondo S. 1967; Isolation and structure of kanamycin inactivated by a cell free system of kanamycin-resistant E coli . Journal of Antibiotics 20:136–141
    [Google Scholar]
26. Vara J., Malpartida F., Hopwood D. A., Jimenez A. 1985; Cloning and expression of a puromycin N-acetyltransferase gene from Streptomyces alboniger in Streptomyces lividans . Gene 33:197–206
    [Google Scholar]