1887

Abstract

A circular linkage map was developed for , a producer of actinomycin C. The map order of various marker loci was deduced from matings and to a minor extent from protoplast fusions. The map strongly resembles that of A3(2). The recombination frequencies were low and highly variable (from 10 to 5 × 10). Plasmid pIJ303 expressed its thiostrepton resistance gene in . but did not promote chromosomal transfer or induce the Ltz phenotype. The data provide a background of genetics for investigations of antibiotic synthesis in this strain.

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1985-05-01
2021-10-19
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