1887

Abstract

Examination of a series of isolates of collected over an 18 month period from a chronic-care patient at Bristol Royal Infirmary revealed the emergence of resistance to carbenicillin. Resistence was mediated by a 47 kb plasmid which transferred by conjugation to a plasmid-free strain of but not to Carbenicillin-sensitive isolates were either plasmid free or contained a 36 kb cryptic plasmid. Restriction endonuclease mapping of this plasmid showed it to be closely related to 32 kb and 34 kb cryptic plasmids reported previously in from Bristol. Mapping of the R plasmid showed it to be derived from the 34 kb cryptic plasmid by transposition of two copies of Tn.

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1985-04-01
2022-01-19
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