1887

Abstract

Summary: The accumulation of amino acids and the excretion of ammonium have been studied in various ammonium assimilation mutants, together with the labelling of glutamine in the presence of [U-C]sucrose when grows on glutamine as the nitrogen source. Ammonium coming from glutamine degradation by the ω-amidase pathway is assimilated by NADP-dependent glutamate dehydrogenase and glutamine synthetase. The operation of these enzymes results in a cycling of glutamine that seems to be essential for cell growth. In addition, glutamine is also converted to glutamate by glutamate synthase.

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/content/journal/micro/10.1099/00221287-131-12-3237
1985-12-01
2021-10-20
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