1887

Abstract

Summary: A degradation pathway for the acetylenic compound 3-butyn-1-ol by a bacterium showing strong resemblance to the physiologically well characterized AM1 is presented. Enzyme studies revealed that the pathway of 3-butyn-1-ol metabolism involves an initial oxidation of the alcohol group by a phenazine methosulphate dependent alcohol dehydrogenase. Subsequently, the aldehyde is probably oxidized to yield 3-butynoic acid. The latter product is hydrated in the absence of cofactors to give acetoacetate which, in turn, is further degraded via acetoacetyl-CoA to acetyl-CoA. The inducible hydration reaction was catalysed by a nonspecific enzyme; hydration of propynoic acid resulted in the formation of malonic semialdehyde.

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/content/journal/micro/10.1099/00221287-131-12-3155
1985-12-01
2019-11-12
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-131-12-3155
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