1887

Abstract

Summary: Ribosomes from are sensitive to puromycin and, to a lesser extent, to the puromycin-precursor -demethyl-puromycin. The puromycin-inactivating enzyme (puromycin -acetyltransferase) from S. alboniger also -acetylates -demethyl-puromycin. This finding indicates that in certain antibiotic-producing organisms the antibiotic-inactivating enzymes may play a role in self-defence against toxic precursor molecules.

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1985-11-01
2021-05-19
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