RT Journal Article SR Electronic(1) A1 Quinn, Rosalind A1 Campbell, Ailsa M. A1 Phillips, A. P.YR 1984 T1 A Monoclonal Antibody Specific for the A Antigen of Brucella spp JF Microbiology, VO 130 IS 9 SP 2285 OP 2289 DO https://doi.org/10.1099/00221287-130-9-2285 PB Microbiology Society, SN 1465-2080, AB Two murine monoclonal antibodies of the IgG3 class have been isolated after immunization with Brucella abortus. An indirect immunofluorescence test was used to screen hybridoma supernatants and subsequently to determine the cross-reactivity of the monoclonal antibodies with other bacteria. One monoclonal antibody reacted with all the smooth Brucella biotypes tried and with Yersinia enterocolitica serogroup O:9, though not with rough Br. ovis or with strains of Escherichia, Proteus, Salmonella, Pseudomonas, Francisella and Bordetella. The other monoclonal antibody displayed a high degree of specificity for brucellae carrying the A lipopolysaccharide-protein surface antigen. The implications for the diagnosis of brucellosis are discussed., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-130-9-2285