1887

Abstract

Two murine monoclonal antibodies of the IgG3 class have been isolated after immunization with An indirect immunofluorescence test was used to screen hybridoma supernatants and subsequently to determine the cross-reactivity of the monoclonal antibodies with other bacteria. One monoclonal antibody reacted with all the smooth biotypes tried and with serogroup O:9, though not with rough or with strains of and The other monoclonal antibody displayed a high degree of specificity for brucellae carrying the A lipopolysaccharide-protein surface antigen. The implications for the diagnosis of brucellosis are discussed.

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1984-09-01
2024-12-12
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