1887

Abstract

The biosynthesis of DNA, proteins, RNA and phospholipids in Mycobacterium smegmatis ATCC 607 was investigated by studying the incorporation of radiolabelled components in the presence of antiserum to mannophosphoinositides. The antiserum had an inhibitory effect on the rate of synthesis of these macromolecules. However, the inhibition was greater when antibody was present together with complement.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-130-7-1795
1984-07-01
2022-01-17
Loading full text...

Full text loading...

/deliver/fulltext/micro/130/7/mic-130-7-1795.html?itemId=/content/journal/micro/10.1099/00221287-130-7-1795&mimeType=html&fmt=ahah

References

  1. Akamatsu Y., Ono Y., Nojima S. 1966; Phospholipid patterns in subcellular fraction of Mycobacterium phlei. Journal of Biochemistry 61:96–102
    [Google Scholar]
  2. Blanden H. A., Evans R. T., Mergenhagen S. E. 1966; Lesions in Escherichia coli membranes after action of antibody and complement. Journal of Bacteriology 91:2377–2381
    [Google Scholar]
  3. David S. D., Wedgewood R. J. 1965; Kinetics of the bactericidal action of normal serum on Gramnegative bacteria. Journal of Immunology 95:75–79
    [Google Scholar]
  4. Folch J., Lees M., Stanley G. H. S. 1957; A simple method for the isolation and purification of total lipids from animal tissues. Journal of Biological Chemistry 226:497–509
    [Google Scholar]
  5. Inoue K., Nojima S. 1967; Immunochemical studies of phospholipids. III. Production of antibody to cardiolipin. Biochimica et biophysica acta 144:409–414
    [Google Scholar]
  6. Khuller G. K., Subrahmanyam D. 1971; Antigenicity of phosphatidylinositomannosides of Mycobacterium tuberculosis. Immunochemistry 8:251–256
    [Google Scholar]
  7. Lachman P. J. 1968; Complement. In Clinical Aspects of Immunology, 2nd edn. p. 339 Edited by Cell P. G. H., Coombs R. R. A. Oxford: Blackwell Scientific Publications;
    [Google Scholar]
  8. Melching L., Vas S. I. 1971; Effect of serum components on Gram-negative bacteria during bactericidal reactions. Infection and Immunity 3:107–115
    [Google Scholar]
  9. Muschel L. H. 1965; Immune bactericidal and bacteriolytic reaction. Cl BA Foundation Symposia pp. 155–168
    [Google Scholar]
  10. Penumarti N., Khuller G. K. 1982; Influence of antibodies to mannophosphoinositides on phospholipid synthesis in Mycobacterium smegmatis ATCC 607. Infection and Immunity 37:884–891
    [Google Scholar]
  11. Razin S., Prescott B., Chonoek R. M. 1970; Immunogenicity of Mycoplasma pneumoniae glycolipids : a novel approach to the production of antisera to membrane lipids. Proceedings of the National Academy of Sciences of the United States of America 67:590–597
    [Google Scholar]
  12. Taneja R., Khuller G. K. 1981; Phospholipid metabolism in Mycobacterium smegmatis ATCC 607 grown at 37 °C and 27 °C. Archives of Microbiology 129:81–84
    [Google Scholar]
  13. Taylor W. 1983; Bactericidal and bacteriolytic activity of serum against Gram-negative bacteria. Microbiological Reviews 47:46–83
    [Google Scholar]
  14. Vishwanathan C. V., Leley V. K. 1976; Simple technique for the development of dry column chromatography. Journal of Chromatography 128:302–303
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-130-7-1795
Loading
/content/journal/micro/10.1099/00221287-130-7-1795
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error