1887

Abstract

Glutamine is shown to be the effector compound for the regulation of both nitrogenase and glutamine synthetase activities in f. sp. . Glutamine synthetase and nitrogenase (components I and II) in this bacterium have similar properties to those from . Ammonia-shock treatment of washed cells, which resulted in an accumulation of [C]glutamine from [C]glutamate, was accompanied by an adenylylation of glutamine synthetase and an inhibition of nitrogenase. Treatment of cells with azaserine (which inhibits glutamate synthase) enhanced the accumulation of labelled glutamine from [C]glutamate and NHC1. Glutamine inhibited the nitrogenase activity of azaserine-treated cells to a greater extent than that of untreated cells.

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1984-05-01
2021-08-02
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