RT Journal Article SR Electronic(1) A1 Clement, Yves A1 Escoffier, Bernard A1 Trombe, Marie Claude A1 Lanéelle, GilbertYR 1984 T1 Is Glutamate Excreted by its Uptake System in Corynebacterium glutamicum? A Working Hypothesis JF Microbiology, VO 130 IS 10 SP 2589 OP 2594 DO https://doi.org/10.1099/00221287-130-10-2589 PB Microbiology Society, SN 1465-2080, AB A strain of Corynebacterium glutamicum used for industrial production of glutamate had uptake systems for l-glutamate and l-serine. These transport systems were inhibited by a protonophore and by an ionophore, indicating that they were driven by a proton-motive force. Cells grown in the presence of an acylated surfactant used in industry to trigger glutamate excretion are known to have a decreased phospholipid content and highly saturated lipids. These surfactant-treated cells were no longer able to accumulate glutamate, while the serine uptake remained undisturbed. As a working hypothesis, it is proposed that the surfactant-induced membrane modifications could specifically result in an uncoupling of the glutamate uptake system, which could consequently be used as a specific excretion system., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-130-10-2589