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Summary: Microscopical examinations of several Lactobacillus bifidus strains have shown that the ‘bifid’ morphology of the cells, which seems to predominate in vivo, is readily changed on subcultivation in different media in vitro. At first highly branched and larger forms occur, and from these mycelial branched filaments develop. The mycelial cells may swell, in which case intensely staining coccoid granules can be detected in the cells. Ultimately, the filaments break up, and give rise to the development of regular short straight rods. Obviously these straight rods appear from the coccoid granules.
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