1887

Abstract

Summary: The effect of D-glucose on growth and erythromycin production by was investigated. -Glucose stimulated growth and caused a strong but temporary suppression of antibiotic formation. Maximum specific suppression of erythromycin formation occurred at a carbohydrate concentration of 20 mg ml. A non-metabolizable analogue of glucose, 2-deoxy--glucose, also suppressed antibiotic formation. Since glucose caused a decrease in erythromycin formation only when added before the stage of antibiotic production, we conclude that this sugar exerted a transient repressive effect on erythromycin biosynthesis.

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/content/journal/micro/10.1099/00221287-128-9-2011
1982-09-01
2019-10-15
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-128-9-2011
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