1887

Abstract

Summary: The pathways of glucose metabolism in closely resemble those described for , in which two discrete systems exist for the uptake of glucose, one periplasmic and oxidative requiring glucose dehydrogenase activity, the second intracellular and phosphorylative. These systems lead to the production of 6-phosphogluconate, which may be metabolized via the Entner-Doudoroff pathway and the pentose phosphate pathway. Terminal oxidation is mediated by the tricarboxylic acid cycle. A mucoid strain of lacked glucose dehydrogenase activity and thus the oxidative pathway was not functional; the pentose phosphate pathway was also inoperative in this strain, as evidenced by the absence of 6-phosphogluconate dehydrogenase activity. Nonmucoid mutants appeared identical to the parent strain; however, a second group of mutants (crenated mutants) were derepressed for both glucose dehydrogenase and 6-phosphogluconate dehydrogenase. Gluconate kinase was not detected in any of the strains studied when grown on glucose; however, growth of the parent strain on gluconate resulted in the induction of this enzyme.

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/content/journal/micro/10.1099/00221287-128-5-981
1982-05-01
2020-01-27
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-128-5-981
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