In yeast, fuchsin resistance at the mitochondrial level is mainly controlled by a nuclear gene (fub). Among the sensitive revertants obtained from a resistant strain of Saccharomyces cerevisiae, different suppression situations have been analysed. A cytoplasmic control of fuchsin resistance was found in one revertant. In two others, two nuclear suppressors have been identified; one of them was linked to the fub gene and exhibited a peculiar cis-trans effect.
BarathZ.,
KunzelH.1972; Cooperation of mitochondrial and nuclear genes specifying the mitochondrial genetic apparatus in Neurospora crassa. Proceedings of the National Academy of Sciences of the United States of America 69:1371–1374
BarrereG.,
MounolouJ. C.1976; Yeast mutants resistant to basic fuchsin: a genetic approach to the integration of nuclear and mitochondrial information. Mutation Research 35:39–52
Bech-HansenN. J.,
RankG. H.1972; Ethidium bromide resistance and petite induction in Saccharomyces cerevisiae. Canadian Journal of Genetics and Cytology 14:681–689
BucherTH.,
NeupertW.,
SebaldW.,
WernerS.1976Genetics and Biogenesis of Chloroplasts and Mitochondria. Amsterdam:: Elsevier/North Holland Biomedical Press.;
CarignaniG.,
LancashireW. E.,
GriffithsD. E.1977; Extrachromosomal inheritance of rhodamine 6G resistance in Saccharomyces cerevisiae. Molecular and General Genetics 151:49–56
ColsonA. M.,
LabailleF.,
GoffeauA.1976; A cytoplasmic gene for partial supression of a nuclear pleiotropic respiratory deficient mutant in petite negative yeast Schizosaccharomyces pombe. Molecular and General Genetics 149:101–109
DeutschJ.,
DujonB.,
NetterP.,
PetrochilloE.,
SlonimskiP. P.,
Bolotin-FukuharaM.,
CoenD.1974; Mitochondrial genetics VI. The petite mutation in Saccharomyces cerevisiae. Interrelations between the loss of the rho+ factor and the loss of the drug resistance mitochondrial genetic markers. Genetics 76:195–219
DujonB.,
SlonimskiP. P.,
WeillW.1974; Mitochondrial genetics IX. A model for recombination and segregation of mitochondrial genomes in Saccharomyces cerevisiae. Genetics 78:425–437
FukuharaH.,
MoustacchiE.,
WesolowskiM.1978; Preferential deletion of a specific region of mitochondrial DNA in Saccharomyces cerevisiae by ethidium bromide and 3-carbethoxypsoralen. Directional retention of DNA sequence. Molecular and General Genetics 162:191–201
GuerineauM.,
GrandchampC.,
PaolettiC.,
SlonimskiP. P.1971; Characterization of a new class of circular DNA molecules in yeast. Bio-chemical and Biophysical Research Communications 42:550–557
HerskowitzI.,
StrathernJ. N.,
HicksJ. B.,
RineJ.1977; Mating-type interconversion in yeast and its relationship to development in higher eucaryotes. In Molecular Approaches to Eucaryotic Genetic Systems pp. 193–202WilcoxG.,
AbelsonJ.,
FoxC. F.
Edited by London:: Academic Press.;
KruszewskaA.,
SzczesniakB.1978; Janus green resistance in Saccharomyces cerevisiae. Interaction of nuclear and cytoplasmic factors. Molecular and General Genetics 160:171–181
LabailleF.,
ColsonA. M.,
PetitL.,
GoffeauA.1977; Properties of a mitochondrial suppressor mutation restoring oxidative phosphorilation in a nuclear mutant of the yeast Schizosaccharomyces pombe. Journal of Biological Chemistry 252:5716–5723
MarcovichH.1953; Rapport entre la structure des acridines et leur activité en tant qu’agents inducteurs de mutants respiratoires chez la levure. Annales de l’Institut Pasteur 85:199–205
MitchellM. B.,
MitchellH. K.1956; A nuclear gene suppressor of a cytoplasmically inherited character in Neurospora crassa. Journal of General Microbiology 14:84–94
PicardG.1978; Non-Mendelian female sterility in Drosophila melanogaster. Sterility in the daughter progeny of SF and RSF females. Biologie cellulaire 31:235–254
PoytonR.O.
1976; The assembly of cytochrome c oxidase from Saccharomyces cerevisiae.
. In Genetics and Biogenesis of Chloroplasts and Mitochondria pp. 207–214BucherTh.,
NeupertW.,
SebaldW.,
WernerS.
Edited by Amsterdam:: Elsevier/North Holland Biomedical Press.;
SevarinoK. A.,
PoyntonR. O.1980; Mitochondrial membrane biogenesis. Identification of a precursor to yeast cytochrome c oxidase subunit II. Proceedings of the National Academy of Sciences of the United States of America 77:142–146
SlonimskiP. P.,
TzagoloffA.1976; Localization in yeast mitochondrial DNA of mutations expressed in a deficiency of cytochrome c oxidase and/or coenzyme QH2 cytochrome c reductase. European Journal of Biochemistry 61:27–41
TrembathM. K.,
MonkB. L.,
KellermanG. M.,
LinnaneA. W.1975; Biogenesis of mitochondria 40. Phenotypic suppression of mitochondrial mutation by a nuclear gene in Saccharomyces cerevisiae. Molecular and General Genetics 140:333–337