1887

Abstract

When carrying a thermosensitive mutation in DNA ligase was grown at the restrictive temperature, several functions associated with the SOS system were induced. These included prophage induction, W-reactivation and W-mutagenesis of ultraviolet-irradiated phage, and protein synthesis, all of which were dependent and chloramphenicol sensitive, and -dependent filamentation. These results indicate that ligase-deficient growth leads to the induction of the SOS system, and that all the above functions may respond to common induction signals.

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1982-03-01
2021-08-01
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