RT Journal Article SR Electronic(1) A1 Crameri, R. A1 Ettlinger, L. A1 Hütter, R. A1 Lerch, K. A1 Suter, M. A. A1 Vetterli, J. A.YR 1982 T1 Secretion of Tyrosinase in Streptomyces glaucescens JF Microbiology, VO 128 IS 2 SP 371 OP 379 DO https://doi.org/10.1099/00221287-128-2-371 PB Microbiology Society, SN 1465-2080, AB In Streptomyces glaucescens, the intracellular and the extracellular enzyme forms of tyrosinase were found to be identical in molecular weight (29000), in copper content (0·21%), in the 19 amino acids at the amino-terminal end and in the ratio of cresolase to catecholase activity (0·005). The tyrosinase secretion process exhibited a constant rate of 0·15 units h−1 (mg protein)−1. Under highly induced conditions intracellular tyrosinase was accumulated. Mutations responsible for the non-melanogenic, tyrosinase-positive non-secretor mutant type are located chromosomally on the upper right arc of the S. glaucescens map near the ade-1 marker., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-128-2-371