Full text loading...
In Streptomyces glaucescens, the intracellular and the extracellular enzyme forms of tyrosinase were found to be identical in molecular weight (29000), in copper content (0·21%), in the 19 amino acids at the amino-terminal end and in the ratio of cresolase to catecholase activity (0·005). The tyrosinase secretion process exhibited a constant rate of 0·15 units h−1 (mg protein)−1. Under highly induced conditions intracellular tyrosinase was accumulated. Mutations responsible for the non-melanogenic, tyrosinase-positive non-secretor mutant type are located chromosomally on the upper right arc of the S. glaucescens map near the ade-1 marker.
Article metrics loading...
Full text loading...
References
Data & Media loading...