1887

Abstract

Observation of the resistance of to the six drugs ampicillin (A), streptomycin (S), tetracycline (T), chloramphenicol (C), kanamycin (K) and sulphadiazine (Su) was made over the 7 years from 1973 to 1979. Strains with ASTCKSu-and ASCKSu-resistance patterns predominated in the years 1973–1975 and 1976–1979, respectively. These resistances were found to be mediated by autotransferring plasmids belonging to the incompatibility group FI . The ASTCKSu-resistance plasmids were unstable, giving rise to deletion variants at a much higher frequency than ASCKSu-resistance plasmids either of natural origin or derived from the ASTCKSu-resistance plasmids. Thus, the ASCKSu-resistance plasmid might be a deletion variant of the ASTCKSu-resistance plasmid. This is supported by the extensive similarity of their cleavage patterns produced by specific restriction endonucleases.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-128-2-239
1982-02-01
2024-04-25
Loading full text...

Full text loading...

/deliver/fulltext/micro/128/2/mic-128-2-239.html?itemId=/content/journal/micro/10.1099/00221287-128-2-239&mimeType=html&fmt=ahah

References

  1. Anderson E.S. 1964; The phage typing of salmonellae other than S. typhi. In The World Problem of Salmonellosis pp. 89–110 Edited by Van Oye E. The Hague: W. Junk;
    [Google Scholar]
  2. Anderson E.S., Threlfall E.J., Carr J.M., Mcconnell M.M., Smith H. R. 1977; Clonal distribution of resistance plasmid-carrying Salmonella typhimurium, mainly in the Middle East. Journal of Hygiene 79:425–448
    [Google Scholar]
  3. Callow B. R. 1959; A new phage typing scheme for Salmonella typhimurium. Journal of Hygiene 57:346–359
    [Google Scholar]
  4. Chau P. Y., Wong W. T., Fok Y. P. 1978; Resistance to chloramphenicol and ampicillin in Salmonella Johannesburg in Hong Kong: observation over a five year period 1973-1977. Journal of Hygiene 81:343–351
    [Google Scholar]
  5. Craigie J., Felix A. 1947; Typing of typhoid bacilli with Vi bacteriophage. Lancet i:823–827
    [Google Scholar]
  6. Greene P. J., Betlach M. C., Boyer H. W., Goodman H. H. 1974; The EcoRI restriction endonuclease. Methods in Molecular Biology 7:387–398
    [Google Scholar]
  7. Hansen J. B., Olsen R. H. 1978; Isolation of large bacterial plasmids and characterization of the P2 incompatibility group plasmids pMGl and pMG5. Journal of Bacteriology 135:227–238
    [Google Scholar]
  8. Humphreys G. O., Willshaw G. A., Anderson E. S. 1975; A simple method for the preparation of large quantities of pure plasmid DNA. Biochimica et biophysica acta 383:457–463
    [Google Scholar]
  9. Mcconnell M. M., Smith H. R., Leonardopoulos J., Anderson E. S. 1979; The value of plasmid studies in the epidemiology of infections due to drug-resistant Salmonella wien. Journal of Infectious Diseases 139:178–190
    [Google Scholar]
  10. Smith H. R., Humphreys G. O., Grindley N. D. F., Grindley J. N., Anderson E. S. 1973; Molecular studies of an fi+ plasmid from strains of Salmonella typhimurium. Molecular and General Genetics 126:143–151
    [Google Scholar]
  11. Threlfall E. J., Carr J. M., Anderson E. S. 1976; Compatibility relations of resistance plasmids in Salmonella typhimurium of Middle Eastern origin. Proceedings of the Society for General Microbiology 3:88
    [Google Scholar]
  12. Willshaw G. A., Smith H. R., Anderson E. S. 1978; Molecular studies of FI me resistance plasmids particularly in epidemic Salmonella typhimurium. Molecular and General Genetics 159:111–116
    [Google Scholar]
  13. Willshaw G. A., Smith H. R., Anderson E. S. 1979; Application of agarose gel electrophoresis to the characterization of plasmid DNA in drug-resistant enterobacteria. Journal of General Microbiology 114:15–25
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-128-2-239
Loading
/content/journal/micro/10.1099/00221287-128-2-239
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error