1887

Abstract

The properties of non-differentiating derivatives of , which appeared spontaneously in continuous cultures of their parental strain, were investigated. These derivatives differ from the original strain by production of only trace amounts of the antibiotic turimycin, inability to form aerial mycelium and spores, and altered morphology of colonies and submerged mycelium. It is proposed that as a consequence of a genetic alteration the derivatives are impaired in a central regulatory function influencing differentiation processes by pleiotropic effects.

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/content/journal/micro/10.1099/00221287-128-11-2687
1982-11-01
2021-07-30
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