SUMMARY: The efflux of Ca from the yeast is induced by the influx of mono- or divalent cations. The mechanism of the tight coupling between K influx and Ca efflux was investigated. Two possibilities were examined: (1) Ca efflux is induced only by the carriermediated and energy-dependent K uptake or (2) Ca efflux can be induced by electric coupling to K influx which is driven by its inward electrochemical gradient in the presence of K ionophores. It was found that K influx in the presence of valinomycin or nigericin and in the absence of glucose did not induce Ca efflux. It is suggested, therefore, that the coupling is mediated by antiport carriers which exchange Ca and K.


Article metrics loading...

Loading full text...

Full text loading...


Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error