@article{mbs:/content/journal/micro/10.1099/00221287-128-1-23, author = "Kelly, Joan M. and Hynes, Michael J.", title = "The Regulation of NADP-linked Isocitrate Dehydrogenase in Aspergillus nidulans", journal= "Microbiology", year = "1982", volume = "128", number = "1", pages = "23-28", doi = "https://doi.org/10.1099/00221287-128-1-23", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-128-1-23", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "The regulation of NADP-linked isocitrate dehydrogenase (NADP-IDH) has been studied in wild-type and mutant strains of Aspergillus nidulans. In the wild-type strain studied, the levels of NADP-IDH vary in a similar way to those of acetamidase, acetyl-CoA synthase, isocitrate lyase and malate synthase under all growth conditions used. Similarly,fac mutants, which are altered in the regulation of these enzymes of acetate utilization, are affected in NADP-IDH levels in a parallel fashion, as are cre mutants, which show altered carbon catabolite repression of this group of enzymes. Possible functions of the NADP-IDH enzyme are considered.", }