Selection for Increased Penicillin Titre Following Hybridization of Divergent Lines of Aspergillus nidulans

References

1. Alikhanian S. I. 1970; Applied aspects of microbial genetics. Current Topics in Microbiology and Immunology 53:91–148
   [Google Scholar]
2. Ball C. 1971; Haploidization analysis in Penicillium chrysogenum. Journal of General Microbiology 66:63–69
   [Google Scholar]
3. Ball C. 1973; The genetics of Penicillium chrysogenum. Progress in Industrial Microbiology 12:47–72
   [Google Scholar]
4. Ball C. 1978; Genetics in the development of the penicillin process. In Antibiotics and Other Secondary Metabolites pp. 165–176 Hütter R., Leisinger T., Núesch J., Wehrli W. Edited by London: Academic Press.;
   [Google Scholar]
5. Calam C. T. 1964; The selection, improvement and preservation of micro-organisms. Progress in Industrial Microbiology 5:1–53
   [Google Scholar]
6. Caten C. E. 1979; Quantitative genetic variation in fungi. In Quantitative Genetic Variation pp. 35–59 Thompson J. N. Jr Thoday J. M. Edited by New York: Academic Press.;
   [Google Scholar]
7. Caten C. E., Jinks J. L. 1976; Quantitative genetics. In Second International Symposium on the Genetics of Industrial Microorganisms pp. 93–111 Macdonald K. D. Edited by London: Academic Press.;
   [Google Scholar]
8. Clutterbuck A. J. 1973; Gene symbols in Aspergillus nidulans. Genetical Research 21:291–296
   [Google Scholar]
9. Cove D. J. 1977; The genetics of Aspergillus nidulans. In Genetics and Physiology of Aspergillus pp. 81–95 Smith J. E., Pateman J. A. Edited by London: Academic Press.;
   [Google Scholar]
10. Davies O. L. 1964; Screening for improved mutants in antibiotic research. Biometrics 20:576–591
    [Google Scholar]
11. Demain A. L. 1973; Mutation and the production of secondary metabolites. Advances in Applied Microbiology 16:177–202
    [Google Scholar]
12. Ditchburn P., Holt G., Macdonald K. D. 1976; The genetic location of mutations increasing penicillin yield in Aspergillus nidulans. In Second International Symposium on the Genetics of Industrial Microorganisms pp. 213–227 Macdonald K. D. Edited by London: Academic Press.;
    [Google Scholar]
13. Elander R. P., Espenshade M. A. 1976; The role of microbial genetics in industrial microbiology . In Industrial Microbiology pp. 192–256 Miller B. M., Litsky W. Edited by New York: McGraw-Hill;
    [Google Scholar]
14. Elander R. P., Espenshade M. A., Pathak S. G., Pan C. H. 1973; The use of parasexual genetics in an industrial strain selection programme with Penicillium chrysogenum. In Genetics of Industrial Microorganisms II pp. 239–253 Vanek Z., Hostálek Z., Cudlin J. Edited by Prague: Academia;
    [Google Scholar]
15. Elander R. P., Chang L. T., Vaughan R. W. 1977; Genetics of industrial microorganisms. Annual Reports on Fermentation Processes 1:1–40
    [Google Scholar]
16. Hamlyn P. F., Ball C. 1979; Recombination studies with Cephalosporium acremonium. In Genetics of Industrial Microorganisms pp. 185–191 Sebek O. K., Laskin A. I. Edited by Washington, D.C.: American Society for Micro-biology;
    [Google Scholar]
17. Hopwood D. A. 1977; Genetic recombination and strain improvement. Developments in Industrial Microbiology 18:9–21
    [Google Scholar]
18. Hopwood D. A., Chater K. F. 1980; Fresh approaches to antibiotic production. Philosophical Transactions of the Royal Society Series B 290:313–328
    [Google Scholar]
19. Hopwood D. A., Merrick M. J. 1977; Genetics of antibiotic production. Bacteriological Reviews 41:595–635
    [Google Scholar]
20. Macdonald K. D. 1966; Differences in diploids synthesized between the same parental strains of Penicillium chrysogenum. Antonie van Leeuwenhoek 32:431–441
    [Google Scholar]
21. Macdonald K. D., Holt G. 1976; Genetics of biosynthesis and overproduction of penicillin. Science Progress 63:547–573
    [Google Scholar]
22. Macdonald K. D., Hutchinson J. M., Gillett W. A. 1964; Properties of heterozygous diploids between strains of Penicillium chrysogenum selected for high penicillin yield. Antonie van Leeuwenhoek 30:209–224
    [Google Scholar]
23. Macdonald K. D., Hutchinson J. M., Gillett W. A. 1965; Heterozygous diploids of Penicillium chrysogenum and their segregation patterns. Genetica 36:378–397
    [Google Scholar]
24. Mather K., Jinks J. L. 1971 Biometrical Genetics, 2nd edn.. London: Chapman and Hall;
    [Google Scholar]
25. Merrick M. J. 1975a; Hybridization and selection for increased penicillin titre in wild-type isolates of Aspergillus nidulans. Journal of General Microbiology 91:278–286
    [Google Scholar]
26. Merrick M. J. 1975b; The inheritance of penicillin titre in crosses between lines of Aspergillus nidulans selected for increased productivity. Journal of General Microbiology 91:287–294
    [Google Scholar]
27. Merrick M. J., Caten C. E. 1975; The inheritance of penicillin titre in wild-type isolates of Aspergillus nidulans. Journal of General Microbiology 86:283–293
    [Google Scholar]
28. Sermonti G. 1959; Genetics of penicillin produc-tion. Annals of the New York Academy of Sciences 81:950–966
    [Google Scholar]
29. Sermonti G. 1969 Genetics of Antibiotic-producing Microorganisms. London: Wiley-Interscience;
    [Google Scholar]
30. Simpson I. N., Caten C. E. 1979a; Induced quantitative variation for penicillin titre in clonal populations of Aspergillus nidulans. Journal of General Microbiology 110:1–12
    [Google Scholar]
31. Simpson I. N., Caten C. E. 1979b; Recurrent mutation and selection for increased penicillin titre in Aspergillus nidulans. Journal of General Microbiology 113:209–217
    [Google Scholar]
32. Simpson I. N., Caten C. E. 1980; Genetics of penicillin titre in lines of Aspergillus nidulans selected through recurrent mutagenesis. Journal of General Microbiology 121:5–16
    [Google Scholar]
33. Soller M. 1980; Optimisation of recurrent selection under mutagenesis in micro-organisms. Heredity 44:295–307
    [Google Scholar]